Rotavirus Gastroenteritis in Children Up to 5 Years of Age. Surveillance Performed in Hospitals From Four Brazilian Regions.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 230
- 主要终点
- The Percentage of Hospitalizations for Diarrhea in Children up to 5 Years of Age
研究概览
简要总结
This is a 1-year study evaluating hospitalizations and the medical care for the treatment of diarrhea from rotavirus infection in children < 5 years of age, conducted in four hospitals located in four Brazilian regions. A stool sample from each eligible child passing 3 or more loose stools or watery stools within a period of 24 hours and requiring hospitalization or rehydration therapy (oral or IV rehydration) will be tested for the presence of rotavirus, using standard laboratory procedures (ie, Enzyme Linked Ligand Sorbent Assay, or ELlSA) by all participating hospitals.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a child < 5 years of age being treated for acute gastroenteritis within 72 hours prior to evaluation in the study hospitals.
- •outpatient children < 5 years of age submitted for treatment of acute gastroenteritis within 72 hours prior to evaluation in the study clinics.
排除标准
- •none specified
结局指标
主要结局
The Percentage of Hospitalizations for Diarrhea in Children up to 5 Years of Age
时间窗: 1 year
The percentage of total hospitalizations for children up to 5 years of age in the 4 Brazilian hospital research centers that were for diarrhea. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
The Geographic Distribution of Hospitalizations for Diarrhea That Are Caused by Rotavirus
时间窗: 1 year
Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. For each geographic location, the number of hospitalizations for diarrhea that was caused by rotavirus was reported.
The Number of Hospitalizations for Diarrhea That Are Caused by Rotavirus by Age Group
时间窗: 1 year
Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. The number of hospitalizations for diarrhea from rotavirus infection was reported for each age group.
The Percentage of Hospitalizations for Diarrhea That Are Caused by Rotavirus
时间窗: 1 year
Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. The number of hospitalizations for diarrhea from rotavirus infection was divided by the total number of hospitalizations for diarrhea in the 4 hospital research centers.
The Number of Hospitalizations for Diarrhea in Children up to 5 Years of Age
时间窗: 1 year
The total number of hospitalizations for diarrhea in children up to 5 years of age in the 4 Brazilian hospital research centers was reported. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
The Numbers of Participants Hospitalized for Diarrhea and Rotavirus-caused Diarrhea Per Month
时间窗: 1 year
Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
The Duration of Hospitalization for Participants Enrolled in the Study
时间窗: From hospital admission to discharge
The mean duration (days) of hospital stay for children up to 5 years of age hospitalized for diarrhea in the 4 Brazilian hospital research centers. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
The Number of Deaths in Hospitalized Participants Enrolled in the Study
时间窗: 1 year
The number of deaths among children up to 5 years of age hospitalized for diarrhea in the 4 Brazilian hospital research centers. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
次要结局
未报告次要终点