Ocular Surface Parameters in Celiac Disease

Not Applicable

Recruiting

• Conditions: Celiac Disease; Inflammatory and Immune System - Autoimmune diseases; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12616001659493
• Lead Sponsor: SB Ankara Ulucanlar Eye Education and Research Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-12-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

We will include the Celiac Disease patients. The diagnosis of Celiac Disease will reached according to the ESPGHAN criteria that had no vitamin deficiency and were using a gluten free diet. Patients and healthy volunteers that are matched for age and gender will include in this study

Exclusion Criteria

Patients and healthy volunteers who were on any kind of medication including corticosteroid and immunosuppressive therapy, who had smoking (smoke more than 1 cigarette per day) and drinking ( >1 standard drink per week) habits, or who had history of systemic and ocular disease will not included in the study

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of tear production assessed using the Schirmer test[1 month post enrolment. ];Stable and healthy tear film assessed using the Tear film break-up time[1 month post enrolment.];Epithelial cell morphology, cytoplasmic and nuclear characteristics and quantify the goblet cell population in the conjunctiva assessed using the Conjunctival impression cytology.<br>This is a composite secondary outcome.[1 month post enrolment.]

Secondary Outcome Measures

Name	Time	Method
one[None]