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临床试验/CTRI/2025/10/095836
CTRI/2025/10/095836尚未招募不适用

Utility Of Rubrics From Homoeopathic Medical Repertory By Dr. Robin Murphy In The Management Of Acne Vulgaris (Grade I, II, III) Among Age Group Of 16-25 Years: An Experimental Non-Controlled Study

Dr Hemangi Vishe1 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2025年10月24日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
34
试验地点
1
主要终点
Outcome will be assessed in terms of

研究概览

简要总结

INTRODUCTION

Acne vulgaris commonly affects individuals aged 16 to 25, impacting their physical and psychological wellbeing. Homoeopathy offers a holistic approach and Dr. Robin Murphy’s repertory provides clinically useful rubrics for acne management. This study aims to evaluate the practical utility and effectiveness of these rubrics in managing Grade I, II and III acne through individualized remedy selection.The inflammatory lesions, namely papules, pustules, nodules and cysts, indicate the severity of the disease. The severity of the acne can be graded on clinical grounds as under

Grade I Mild Comedones, occasional papules

Grade II Moderate Comedones, many papules, few pustules.

Grade III Severe Predominantly pustules, nodules and abscesses.

Grade IV Cystic Mainly Cysts or abscesses, widespread scarring

Homoeopathic Medical Repertory, a modern alphabetical repertory is mainly based on ‘Repertory of the Homoeopathic Materia Medica by Dr. J.T. Kent and Repertory of Hering’s Guiding Symptoms of our Materia Medica by Dr. C.B. Kneer. remedies. Dr. Robin Murphy’s Homoeopathic Medical Repertory is a clinically oriented repertory that blends classical and modern perspectives, offering a practical framework for repertorization based on symptom totality. Despite its widespread use in clinical practice, there is limited research evidence evaluating the utility and effectiveness of rubrics from this repertory in managing acne vulgaris.

AIM AND OBJECTIVE

Primary Objective To study the utility of rubrics from Homeopathic Medical Repertory by Dr. Robin Murphy in Management of Acne Vulgaris Grade I II III among age group of 16  to 25 years.

Other objective

1 To study clinical presentation of Acne Vulgaris Grade I II III among age group of 16 to 25 years.

2 To compare the patient pretreatment score and posttreatment score for Acne Vulgaris Grade I II III on GAGS Scale among age group of 16 to 25 years.

METHODOLOGY

1. Type of study design An Experimental Noncontrolled Study.

2. SettingThe study will be conducted at the OPD of the institution.

3. Duration of the study 18 months

4. Method of selection of study subjects

Inclusion Criteria

1.Clinically diagnosed cases of Acne Vulgaris Grade I II III

  1. Patients of age group 16 to 25 years.

  2. Patients of All Genders.

Exclusion Criteria

  1. Grade IV Acne Vulgaris.

  2. All other variants of acne like Acne conglobate, Acne fulminans, Acne excoriee etc.

  3. Patient with complications of Acne Vulgaris like scarring.

  4. Patient taking any other local or tropical medications for Acne Vulgaris.

  5. Lactating Women or Pregnant Women.

  6. Suspected immuno compromised cases.

Subject withdrawal criteria

Patients who do not wish to continue the treatment.

  1. Patients who do not follow up regularly.

  2. Patient developing any Medical Emergency.

Specification of instruments and related measurements:

  1. Homoeopathic Case Taking Proforma will be used in each case.

  2. Outcome assessment tool Prevalidated GAGS Scale will be used.

Outcome assessment criteria

a Outcome will be assessed in terms of

Improved if grades of improvement are fair,good or excellent or  greater than or equal to 25 percentage

Not improved if grades of improvement are poor or worse or less than 25 percentage

b) Outcome Pre and Post treatment according to GAGS scale.

Improvement was graded according to the 5 point Global Assessment Scale (GAS).

Grades of improvement by reduction in 5 point global assessment scale (GAS)

1.     Excellent  greater than or equal to 75 percentage improvement in GAS

2.     Good  50 percentage to 74 percentage improvement in GAS

3.     Fair 25 percentage to 49 percentage improvement in GAS

4.     Poor less than 25 percentage improvement in GAS

5.     Worse  Result worse than pre treatment finding.

Sample size 34 patients will be selected.

Sampling technique Nonprobablity Purposive sampling based on inclusion and exclusion criteria

Data management and analysis procedure

1.      Duration of study 18 months

2.     Duration of each  case  Each case will be studiedd upto 6 months or till recovery occurs, whichever is earlier.

3.     Duration of follow up ease case 15 days and earlier if required.

Clinical outcome assessment will be done at baseline of 1 month, 3 months and 6 months

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
16.00 Year(s) 至 25.00 Year(s)(—)

入选标准

  • Inclusion Criteria: 1.Clinically diagnosed cases of Acne Vulgaris (Grade I, II, III)
  • Patients of age group 16 to 25 years.
  • Patients of All Genders.

排除标准

  • Exclusion Criteria:
  • Grade IV Acne Vulgaris.
  • All other variants of acne like Acne conglobate, Acne fulminans, Acne excoriee etc.
  • Patient with complications of Acne Vulgaris like scarring.
  • Patient taking any other local or tropical medications for Acne Vulgaris.
  • Lactating Women or Pregnant Women.

结局指标

主要结局

Outcome will be assessed in terms of

时间窗: 1 Duration of study- 18 months | 2 Duration of each case- Each case will be studied for 6 months or till recovery occurs, whichever is earlier. | 3 Duration of follow up- ease case 15 days and earlier if required. | 4 Clinical outcome assessment will be done at baseline of 1 month, 3 months and 6 months

1 Improved

时间窗: 1 Duration of study- 18 months | 2 Duration of each case- Each case will be studied for 6 months or till recovery occurs, whichever is earlier. | 3 Duration of follow up- ease case 15 days and earlier if required. | 4 Clinical outcome assessment will be done at baseline of 1 month, 3 months and 6 months

2 Not improved

时间窗: 1 Duration of study- 18 months | 2 Duration of each case- Each case will be studied for 6 months or till recovery occurs, whichever is earlier. | 3 Duration of follow up- ease case 15 days and earlier if required. | 4 Clinical outcome assessment will be done at baseline of 1 month, 3 months and 6 months

These outcome will be assessed as per Pre and Post treatment score according to GAGS scale.

时间窗: 1 Duration of study- 18 months | 2 Duration of each case- Each case will be studied for 6 months or till recovery occurs, whichever is earlier. | 3 Duration of follow up- ease case 15 days and earlier if required. | 4 Clinical outcome assessment will be done at baseline of 1 month, 3 months and 6 months

次要结局

  • not applicable(not applicable)

研究者

发起方
Dr Hemangi Vishe
申办方类型
Other [Self Sponsored]
责任方
Principal Investigator
主要研究者

Dr Hemangi Vishe

Dr G D Pol Foundation Ymt Homoeopathic Medical College Hospital And PG Institute

研究点 (1)

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