Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild to Moderate Acne Vulgaris
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Effectiveness of 25 % trichloroacetic acid peel versus 30 % salicylic acid peel in the treatment of mild to moderate acne vulgaris
研究概览
简要总结
To compare the efficacy of 25% trichloroacetic acid peel versus 30% salicylic acid peel in mild to moderate acne vulgaris.
Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from 01 Jun 2022 to 30th Nov, 2022.
Methodology: A total of 60 patients presented with mild or moderate acne vulgaris were randomized into two groups comprising 30 patients in each group and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Patients in Group A were treated with 25% TCA peel whereas patients in Group B were treated with 30% SA peel. At the end of therapy after 12 weeks, evaluation of active acne was done by individual lesion counts (comedones, papules and pustules) and calculation of the Michaelsson acne score (MAS).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 22 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with mild or moderate facial acne vulgaris presented in dermatology opd
排除标准
- •Patients with grade III or IV acne vulgaris
- •patients taking any acne medications or had taken oral or topical medications in the past 4 weeks
- •pregnant female patients or nursing a baby
- •patients with known hypersensitivity to the formulations used in the study or a history of photosensitivity
- •hypertrophic scars, keloidal tendency, active or recurrent herpes simplex infection
- •active dermatosis
- •unrealistic expectations
研究组 & 干预措施
Group A 25% TCA
25% TCA peel Patients of group A were treated with 25% TCA peel and patients at 2-week intervals for a total of 12 weeks. Clinical evaluation was done at the end of therapy after 12-weeks of treatment.
干预措施: 25% TRICHLOROACETIC ACID (Drug)
Group B 30% SALICYLIC ACID
30% SA peels Patients of group B were treated with 30 % salicylic acid peel and patients at 2 weeks interval for a total of 12 weeks.clinical evaluation was done at the end of therapy after 12 weeks of treatment
干预措施: 30% salicylic acid (Drug)
结局指标
主要结局
Effectiveness of 25 % trichloroacetic acid peel versus 30 % salicylic acid peel in the treatment of mild to moderate acne vulgaris
时间窗: 12 weeks
Michaelson acne scores (MAS) Michaelson acne scores (MAS) was used to measure the effectiveness of both peels
次要结局
未报告次要终点
研究者
Dr kiran gul
principal investigator
Combined Military Hospital Abbottabad