Use of TCA 15% + 3% Glycolic Acid Chemical Peel for Improvement in Hand Lentigines
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Improvement in hand lentigines on a 5-point scale
研究概览
简要总结
This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).
详细描述
This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.
A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.
Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.
Four to six weeks after their final treatment, subjects will return for photography.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 22 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No laser, chemical peel, neuromodulator, filler treatment to the hands in >3 months
- •At least 5 lentigines on each hand
排除标准
- •Pregnancy
- •Breastfeeding
- •Allergy to trichloroacetic acid
- •Allergy to glycolic acid
- •Open wounds on treatment area (hands)
- •Active inflammatory disease on treatment area such as atopic dermatitis, psoriasis, dermatomyositis
研究组 & 干预措施
Treatment
Treatment of hand lentigines with 15% trichloroacetic acid + 3% glycolic acid
干预措施: 15% Trichloroacetic acid + 3% glycolic acid (Drug)
结局指标
主要结局
Improvement in hand lentigines on a 5-point scale
时间窗: 4-6 weeks after last treatment
Photos will be graded on a 5 point scale (0=no change, 1=1-25% change, 2=26-50% change, 3=51-75% change, 4=76-100% change)
次要结局
- Improvement in hand lentigines using the Global Aesthetic Improvement Scale(4-6 weeks after last treatment)
研究者
Kachiu Lee, MD
Principal Investigator
Main Line Center for Laser Surgery