跳至主要内容
临床试验/NCT03281512
NCT03281512已完成不适用

Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight in the China Health and Nutrition Survey (CHNS)

Zhejiang University0 个研究点目标入组 14,383 人开始时间: 2017年9月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
14,383
主要终点
Mortality

研究概览

简要总结

The role of saturated fatty acids (SFAs) intake in the development of total death, cardiovascular diseases, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is scant.The investigators aim to use the data from the China Health and Nutrition Survey to assess the long-term association of SFAs intake with total mortality, diabetes, hypertension and overweight.

详细描述

The role of saturated fatty acids (SFAs) intake in the development of total death, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is lacking.The investigators aim to utilize the data from the China Health and Nutrition Survey. The investigators will calculate the cumulative average intake of SFAs based on 3 consecutive 24-h dietary recalls in each round.Sex-specific Cox regression models will be used to estimate the relative risk.Results from our work will be used to provide epidemiological evidence for improving recommendation on SFAs intake for Chinese in dietary guidelines.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged ≥20 with complete data on diet and follow-up time

排除标准

  • Cardiovascular diseases
  • Diabetes (for analyses of diabetes)
  • Body mass index ≥ 24 kg/㎡ (for analyses of overweight)
  • Hypertension (for analyses of hypertension)

结局指标

主要结局

Mortality

时间窗: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years

Incidence of all-cause death, on basis of household members' report

Diabetes

时间窗: From entry into the study (baseline: 1997-2009) until 2011

Incidence of diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%

次要结局

  • Hypertension(From entry into the study (baseline: 1997-2009) until 2011)
  • Saturated fatty acids intake(From entry into the study (baseline: 1997-2009) until 2011)
  • Overweight(From entry into the study (baseline: 1997-2009) until 2011)

研究者

发起方
Zhejiang University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jingjing Jiao

Associate Professor

Zhejiang University

相似试验