An evaluation of efficacy and safety of Statin versus Bempedoic acid versus Bempedoic acid added Ezetemibe in dyslipidemic North Indian population.

Phase 4

Not yet recruiting

• Conditions: Mixed hyperlipidemia,

• Registration Number: CTRI/2025/04/084658
• Lead Sponsor: Institute of Medical Sciences Banaras Hindu University

Brief Summary

Dyslipdemia is a global health concern due to major cardiovascular impact . statins are the corner stone of prevention and treatment of Cardiovascular disease but can produce statin associated muscle weakness. there is no universally accepted defination  for statin intolerance. Statin associated muscle symptoms are an important clinical problem, causing discontinuation of treatment leading to harmful impact on health. the present study will compare the efficacy and safety of Bempedoic acid  monotherapy (180mg daily dose) and fixed dose combination Bempedoic acid with Ezetimibe versus statin (10mg).

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-05
• Last Update Posted: 2025-03-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

dyslipidemic patients.

Exclusion Criteria

pregnancy, lactation, renal failure, severe hepatic dysfunction, neurological disorders, on immunosuppressants.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
lipid profile, hsCRP, CPK-total, HbA1c. BMI, LFT, RFT.	base line , 4 , 8 and 12 weeks of treatment

Trial Locations

Locations (1)

Sir sunderlal hospital-BHU; 🇮🇳 Varanasi, UTTAR PRADESH, India

Sir sunderlal hospital-BHU

🇮🇳Varanasi, UTTAR PRADESH, India

Dr Ved Prakash

Principal investigator

8601741409

sonivedgmc@bhu.ac.in