The effect of Ondansetron to tretment obsessive -copmpulsive disorder
Phase 3
- Conditions
- Obsessive -compulsive disorder.F42-The essential feature is recurrent obsessional thoughts or compulsive acts.obsessional thoughts are ideas,images,or impuses that enter the patients mind again and again in stereotyped form.They are , almost invariably distressing and the patient ofte
- Registration Number
- IRCT20170723035247N1
- Lead Sponsor
- Vice chancellor for resaerch Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Aged 18 years and over.
Despite received at least three months of adequate and tolerable SSRI drugs, the scores of obsessive-compulsive scores 16 and up.
No pregnancy or breastfeeding in women.
No psychiatric disorder such as Bipolar in the axis 1 of psychiatry.
Lack of mental retardation in the axis 2 of psychiatry.
Lack of alcohol intake 6 months before the study.
Lack of psychotherapy during the study.
Exclusion Criteria
Acute and severe physical illness during the study.
Non-follow-up for 4 weeks.
Severe complications during treatment.
Not using contraceptive methods in females
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity obsessive compulsion. Timepoint: Before the start of trial and every four weeks. Method of measurement: Yale Brown Obsessive -Compulsion Scala.
- Secondary Outcome Measures
Name Time Method Sudden drug effect. Timepoint: Before the start of the trial ,the end of the first-two-fourth-sixth-eighth-twelfth weeks. Method of measurement: Interviwe and examination.