Flying Intervention Team for Endovascular Treatment of Acute Ischemic Stroke in Rural Areas

• Conditions: Brain Infarction

• Registration Number: NCT04270513
• Lead Sponsor: Munich Municipal Hospital

Brief Summary

The aim of this study is to compare time delay and safety parameters of stroke patients initially admitted to a rural primary stroke center (PSC) who receive endovascular treatment (EVT) by a Flying Intervention Team with patients who receive EVT after secondary transfer to a comprehensive stroke center (CSC).

Detailed Description

A novel health care concept was implemented in the telemedical stroke network TEMPiS (Telemedical Project for integrative Stroke Care) to reduce time delays to EVT in stroke patients with large vessel occlusion: After telemedicine-assisted identification of EVT candidates in a PSC, a Flying Intervention Team (neuroradiologist and angiography assistant) is flown from a CSC via helicopter to the PSC to perform EVT in the local angiography suite. Flying Intervention Team service runs from 8 a.m. to 10 p.m. Patients remain at local stroke unit for further treatment.

Analysis will include time delay to EVT, recanalization, symptomatic intracerebral hemorrhage, periprocedural complications, in-hospital complications, and mortality.

Study Timeline

• Study Start: 2018-02-01
• Study First Submitted: 2018-04-13
• Primary Completion: 2019-10-24
• Status Verified: 2020-02
• Study First Submitted QC: 2020-02-12
• Last Update Submitted: 2020-02-12
• Study First Posted: 2020-02-17
• Last Update Posted: 2020-02-17
• Study Completion: 2020-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 477

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time from decision for endovascular treatment to groin puncture	day 1	Time from telemedicine-assisted decision for endovascular treatment to initiation of endovascular treatment by groin puncture

Secondary Outcome Measures

Name	Time	Method
Periprocedural complications	day 1	Proportion of patients with periprocedural, endovascular treatment associated complications
Symptomatic intracerebral hemorrhage	7 days	Proportion of patients with symptomatic intracerebral hemorrhage
In-hospital death or palliative care	7 days	In-hospital death or decision for palliative care
In-hospital complications	7 days	Proportion of patients with other in-hospital complications
Time from symptom onset to recanalization	day 1	Time from symptom onset to recanalization of previously occluded target artery by endovascular treatment
Other procedural times of hyperacute care	day 1	Other procedural times between symptom onset, admission to PSC, first imaging, decision for endovascular treatment, initiation of endovascular treatment and completion of endovascular treatment
Recanalization	day 1	Proportion of patients with antegrade reperfusion of more than half of the previously occluded target artery ischemic territory after endovascular treatment

Trial Locations

Locations (1)

TEMPiS TeleStroke Network, Department of Neurology, Munich Municipal Hospital; 🇩🇪 Munich, Bavaria, Germany