Clinical Results Of Platelet Rich Plasma (PRP) Injections For Knee Osteoarthritis (KOA), Our Experience At Midterm Follow Up
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 153
- 试验地点
- 1
- 主要终点
- Change in Visual Analogic Scale
研究概览
简要总结
It was conducted a prospective study with a series of 153 patients treated with PRP injections in patient affected by knee osteoarthritis. One independent observer performed clinical and functional evaluations at T0 (recruitment), T1 (one month after the injection), T2 (three months after the last injection) and T3 (six months after the last injection).
The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Knee Score Society (KSS) score and the Visual Analogue Scale (VAS) were evaluated and recorded for each patient at each follow up.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 81 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 40 and 81;
- •Body mass index (BMI) between 21.5 and 29.3;
- •Chronic history (for at least 4 months) of knee joint pain;
- •Radiographically documented knee osteoarthritis of grades 1 to 3 (Kellgren-Lawrence (K-L) radiographic classification scale)
排除标准
- •Radiographically severe documented knee osteoarthritis of grade 4 (K-L radiographic classification scale);
- •Previous femur and tibia fractures;
- •Knee previous surgical treatment (e.g., arthroscopy);
- •Hyaluronic acid infiltration within the previous six months;
- •Hemoglobin levels <10 g/dL;
- •History of oncohematological disease, infections, or immunodepression
结局指标
主要结局
Change in Visual Analogic Scale
时间窗: Day 0; Month 1; Month 3; Month 6 (after the injection)
The knee pain was quantified using the Visual Analogic Scale ranging from 0 (no pain) to 10 (worst imaginable pain).
次要结局
未报告次要终点