NCT04918108已完成不适用
Inflammatory Response and Anti-inflammatory Action for Aortopathy & Arteriopathy (5A-Plan): A Multicenter Cohort Study
Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2021年1月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- 30-day mortality
研究概览
简要总结
Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •acute type Aortic dissection;
排除标准
- •Iatrogenic aortic dissection OR traumatic aortic dissection
- •Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases.
- •Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.
研究组 & 干预措施
inflammatory subphenotype
干预措施: inflammatory response (Biological)
结局指标
主要结局
30-day mortality
时间窗: 30 days after surgery
any cause death within 30 days of surgery
次要结局
- ICU mortality(7 days after surgery)
研究者
Hong Liu
Investigator of Nanjing Medical University
Nanjing Medical University
研究点 (1)
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