Transfusion to protect the vessels functio
Phase 1
- Conditions
- Acute critical illnes requiring volume resuscitation with fluids (e.g. Sepsis).Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]
- Registration Number
- EUCTR2020-005045-17-NL
- Lead Sponsor
- AMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 24
Inclusion Criteria
- Healthy male volunteer
- Between 18-35 years old
- BMI between 20-25
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 24
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- No informed consent
- Any abnormal lab or urine test result during the screening prior to inclusion of the study
- Use of medication on prescription - Blood donation < 3 months
- Previous blood transfusion
- Participation in other medical study < 3months
- Participation in previous volunteer studies using LPS in the past year
- Fever at the intake or on research day (T > 38.5)
- Known allergic reaction to albumin
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method