Detection of Ileoanal Pouch/Reservoir Adenomas
- Conditions
- Adenomatous Polyps
- Interventions
- Procedure: Adenomas detection rate with the different observation methods
- Registration Number
- NCT05954949
- Lead Sponsor
- Jean Christophe Saurin
- Brief Summary
The detection of adenomas is the basis for the follow-up of patients with familial adenomatous polyposis, after colectomy, with a remnant rectum or an ileal pouch. The optimal method for the adenomas detection is not defined yet. Despite the proven effectiveness of indigo-carmine in different indications dye chromoendoscopy is not used in a consensual way at the international level. The situation of the ileal pouch is specific as adenomas have a usually flat shape and are much more difficult to identify than in the situation of a remnant rectum, even in the situation of \> 5 mm adenomas that should be resected.
Our hypothesis is that indigo-carmine can improve adenomas detection, including \> 5 mm adenomas, in patients with a an ileal pouch after colectomy improving the effectiveness of surveillance programs and potentially reducing the risk of cancer in this population.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 40
- Patients with familial adenomatous polyposis
- Ileo-anal anastomosis with pouch reservoir
- Quality of the final preparation = 3 (excellent) on the studied area
- Films made under optimal conditions for the 3 staining methods
- Patient with no familial adenomatous polyposis
- Patient without Ileo-anal anastomosis reservoir
- Insufficient quality of the final preparation <3
- Absence of films made under optimal conditions for the 3 staining methods
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Ileoanal pouch adenomas detection assessment Adenomas detection rate with the different observation methods Every patient who needs follow up lower digestive examination for familial adenomatous polyposis after colectomy can join this study with ileal pouch adenomas detection by experienced endoscopist.
- Primary Outcome Measures
Name Time Method Average number of ileal pouch/reservoir adenomas 6 months after colonoscopy Average number of ileal pouch/reservoir adenomas detected according to the endoscopic mode (staining or not, virtual or not) based on a paired review of the films with final consensus in case of discordance
- Secondary Outcome Measures
Name Time Method