Mindfulness Meditation Combined With Progressive Muscle Relaxation Training for Uremic Sarcopenia
- Conditions
- Hemodialysis Patients With Sarcopenia
- Interventions
- Behavioral: The mindfulness meditation combined with progressive muscle relaxation training .
- Registration Number
- NCT06261372
- Lead Sponsor
- Ningbo Medical Center Lihuili Hospital
- Brief Summary
To study the effect of mindfulness meditation combined with progressive muscle relaxation training on clinical efficacy and quality of life in maintenance hemodialysis (MHD) patients with sarcopenia. Eligible sarcopenic patients in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group received mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks.To observe whether the combined intervention training can improve the motor ability and quality of life of patients with sarcopenia in a short period of time.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 49
- Patients who met the sarcopenia criteria established by the Asian Working Group for Sarcopenia (AWGS) in 2014
- Stable condition and generally good health status
- Good compliance and ability to collaborate well with the physician
- Undergoing hemodialysis three times per week for at least three months, with a KT/V ≥ 1.2
- No significant cardiovascular or cerebrovascular complications (such as severe heart failure, severe arrhythmias, angina, and cerebrovascular diseases)
- Patients with sarcopenia who met the clinical diagnostic criteria were selected to ensure the quality of the included patients
- Inability to complete handgrip strength, 6-meter walk test, 10 sit-to-stand tests, and the use of bioelectrical impedance analysis (BIA) due to contraindications
- Coexistence of mental illness or severe cognitive or communication disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description intervention group The mindfulness meditation combined with progressive muscle relaxation training . In addition to conventional treatment, mindfulness meditation combined with progressive muscle relaxation training was implemented during the interdialytic period.
- Primary Outcome Measures
Name Time Method KDQOLTM(Kidney Disease Quality of Life short Form) score 3 months The KDQOLTM score is between 0 and 100, and the higher the score, the better the health
high-sensitivity C-reactive protein (hsCRP) 3 months hsCRP represents an inflammatory marker, and its concentration ranges from 0.0 to 10mg/L.
albumin(ALB) 3 months Albumin represents a nutritional indicator, and its concentration ranges from 40 to 55g/L.
10 sit-to-stand test in seconds 3 months The 10 sit-stand test represents exercise ability, and the shorter the time, the greater the exercise ability.
interleukin-6 (IL-6) 3 months Interleukin 6 represents an inflammatory marker, and its concentration is 20pg/ml or less.
prealbumin (PA） 3 months Prealbumin represents a nutritional indicator, and its concentration ranges from 0.20 to 0.43g/l.
Grip strength in kilograms 3 months Grip strength represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero, and its maximum value is unlimited.
6-meter walk test in metre per second 3 months 6-meter walk test represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero metre per second, and its maximum value is unlimited.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Li Huili Hospital, Ningbo Medical Center
🇨🇳Ningbo, Zhejiang, China