Bone Turnover and Lipid Metabolism in Response to Vagal Nerve Stimulatio

Completed

• Conditions: botmetabolisme; bone turnover; lipid metabolism; 10013317

• Registration Number: NL-OMON37555
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Patients eligible for vagal nerve stimulator implantation
Age >18 years

Exclusion Criteria

Incapability of giving informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Bone turnover: The main outcome parameter is the change of serum concentrations<br /><br>of bone turnover markers (procollagen type I N propeptide (P1NP) and C-terminal<br /><br>crosslinking telopeptides of collagen type I (CTX)).<br /><br>Lipid metabolism: The main outcome parameter is the change of the plasma lipid<br /><br>profile (cholesterol, LDL, HDL, triglycerides).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>