ow Energy Availability (LEA) Threshold in Male Athletes

Not Applicable

Completed

• Conditions: Low energy availability; ow energy availability; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621001284853
• Lead Sponsor: ational Institute of Education, Nanyang Technological University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-23
• Study Completion: 2021-10-01
• Last Update Posted: 12 September 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

1) Male
2) Age: 21-35 years
3) Complete at least 3 running sessions/week on a regularly basis
4) Running at least 24km a week on a regular basis
5) Self-reported weight stable (±3 kg) in the past three months and not actively trying to lose weight by self-report
6) Body mass index: 19-25 kg·m-2
7) Normal blood pressure (less than 120/80 mmHg and greater than 90/60 mmHg)
8) Normal blood glucose level (less than 6.0 mmol/ L and greater than 3.9 mmol/L)
9) Healthy, injury-free (e.g. no cardiovascular disease, diabetes mellitus, orthopaedic impairment that interferes with moderate-to-vigorous exercise)
10) No previous or current diagnosis of eating disorder(s)/No known or deliberate disordered eating behaviours
11) No special diets (e.g. vegan, vegetarian, ketogenic diet)
- Halal dietary requirements is acceptable
12) Non-smoker

Exclusion Criteria

1) Any diagnosed form of cardiometabolic disease (cardiovascular disease, diabetes, metabolic syndrome, hypertension)
2) Any symptoms contraindication of exercise testing (eg chest pains)
3) Any balance or dizziness problems
4) Any chronic medical conditions (whether medicated or not)
5) Any bone joint problems
6) Any Physician diagnosed contraindications to exercise
7) If you drink alcohol more than 3 times each week and more than 3 drinks each time
8) Tick Yes to any questions in Part 1 of the Physical Activity Readiness Questionnaire Plus.
9) Any allergies to food items used in the prescribed meals.
10) A score on the Sick, Control, One, Fat, Food (SCOFF) questionnaire of 2 or more.
11) A score on the Exercise Addiction Inventory of 24 or more.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in resting metabolic rate (RMR) measured via indirect calorimetry (ventilated hood dilution method)[RMR will be measured on Day 1 and Day 5 of each trial condition.];Change in bone resorption marker ß-CTX (ß-carboxyterminal cross-linked telopeptide of type I collagen), bone formation marker P1NP (propeptide of type I procollagen) and osteocalcin (Oc), assessed using blood samples. A 10ml sample of venous blood will be taken from an antecubital vein, and dispensed into a silicon-coated vacutainer tube, ethylenediaminetetraacetic acid (EDTA) tube, The sample will be centrifuged at 3500rpm, 20 degree celcius,for 11 minutes. The plasma will be pipetted off and frozen at -86?Celsius for subsequent analyses.[Blood samples will be drawn on Day 1 and Day 5 of each trial condition.]

Secondary Outcome Measures

Name	Time	Method
Change in body mass will be measured with Inbody 720, InBody, South Korea.[Body mass will be measured on Day 1 and Day 5 of each trial condition.];Change in body fat percentage will be measured with Inbody 720, InBody, South Korea.[Body fat percentage will be measured on Day 1 and Day 5 of each trial condition.];Change in mood score measured by the Brunel Mood Scale[Mood score will be measured on Day 1 and Day 5 of each trial condition.]