NCT01543386已完成1 期
Effects of Curcumin Loading Dose on Vascular Reactivity of Healthy Middle-aged Smokers
University Hospital, Clermont-Ferrand1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2012年2月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Changes in brachial Flow Mediated Dilatation
研究概览
简要总结
The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk
详细描述
The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 50 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •50 to 70 year-old volunteers
排除标准
- •treated hypertension
- •treated hypercholesterolemia
- •chronic disease
- •vegetarian or other unusual diets
- •chronic alcoholism
研究组 & 干预措施
curcumin
Other
The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk
干预措施: Curcumin (Drug)
结局指标
主要结局
Changes in brachial Flow Mediated Dilatation
时间窗: at Visit 1 (Day 0) and visit 2 (Day3/day5)
次要结局
- Changes in fingertip arterial tonometry(at visit 1 (day 0) and visit 2 (day3/day5))
- Modifications of leukocytes transcriptome(at visit 1 (day 0) and visit 2 (day3/day 5))
研究者
研究点 (1)
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