Screening Tool to Identify the Dominant Pain Mechanism in Cancer Survivors: PainsCan
- Conditions
- Cancer PainCancer Survivors
- Registration Number
- NCT03981809
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Brief Summary
Development and internal validation of an easy-to-use tool for clinical pain assessment. The tool has to be applicable in any clinical practice and without the need for expensive and complicated hospital tools to identify the source of persistent pain after the treatment of cancer.
- Detailed Description
An adequate selection of physiotherapy treatment for persistent pain after the treatment of cancer, depends highly on the mechanism of the pain.
Pain can arise from a damaged nerve or tissue (skin, lymphatic system...). But when pain becomes chronic, alterations to the central nervous system can occur, as regulations of the facilitating and inhibiting mechanisms. These alterations may cause central sensitization pain. The body is now sensitized and cannot distinct harmful from harmless stimuli.
Each type of pain requires a specific treatment, therefore identification of the pain mechanism is crucial. Up till now, expensive and complex tests were performed in a hospital setting to determine if a patient suffers from neuropathic, nociceptive or central sensitization pain. This study aims for developping an assessment tool that does not require expensive devices but can be easily performed by any physiotherapist, within the timeframe of a standard consultation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 92
- Patient treated for primary cancer: breast, prostate, lung/bronchus, colon/rectum, gynecologic (uterus or ovary)
- Complete remission
- Curative treatment finished
- Ongoing hormonal and targeted treatment permitted
- Patient experiences pain (NRS minimum 3/10 during the past week)
- Active metastasis
- Palliative status
- Other type of cancer than mentioned in inclusion criteria
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Conditioned pain modulation 10 minutes Central sensitization pain: pain caused by changes in the central nervous system is assessed with a thermal test (2)
Temporal summation 2,5 minutes Central sensitization pain: pain caused by changes in the central nervous system is assessed with a series of touch stimuli (3)
Diffuse pain 0,5 minute Central sensitization pain: pain caused by changes in the central nervous system is assessed by painting affected areas on a body chart (4)
Joint pain 30 seconds Nociceptive pain: pain that arises from a damaged tissue is assessed by examining if several joints are sore, especially in the morning (3)
Manual palpation 3 minutes Central sensitization pain: pain caused by changes in the central nervous system is assessed by applying pressure with manual palpation (5)
Passive mobility 3,5 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by examining the movements the clinician can perform on the patient (5)
Douleur Neuropathic 4 questions (DN4) questionnaire 2 minutes Neuropathic pain: pain that arises from a damaged nerve is assessed with a questionnaire (1)
Quantitative sensory testing 20 minutes Neuropathic pain: pain that arises from a damaged nerve is assessed by measuring thermal thresholds (2)
Lymphedema 4 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by examining the presence of lymphedema by measuring the circumference of the arm (2)
Active mobility 2,5 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by examining the movements the patient can perform (4)
Strength 1,5 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by the strength the patient can perform in a specific movement (6)
Central Sensitization Inventory (CSI) questionnaire 5 minutes Central sensitization pain: pain caused by changes in the central nervous system is assessed with a questionnaire (1)
Scar tissue 2 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by examining the elasticity of the scar tissue by manual palpation of the clinician (7)
Pain mapping 1 minute Neuropathic pain: pain that arises from a damaged nerve is assessed by painting affected areas on a body chart (3)
Evaluation of skin 20 seconds Nociceptive pain: pain that arises from a damaged tissue is assessed by visual evaluation of the skin condition (1)
Axillary web syndrome 2 minutes Nociceptive pain: pain that arises from a damaged tissue is assessed by visually examining the presence of lymph cords in the axilla (8)
- Secondary Outcome Measures
Name Time Method Pain questionnaire 30 seconds Brief Pain Inventory
Pain disability: Pain Disability Index 3 minutes Pain Disability Index
Pain intensity: Visual Analogue Scale 1 minute Visual Analogue Scale at the moment, worst and least pain during the past week
Pain Self-efficacy and Expectations: questionnaire 5 minutes Pain self-efficacy and expectations questionnaire
Pain catastrophizing scale 6 minutes Pain catastrophizing scale
Depression, anxiety and stress 7 minutes Depression Anxiety and Stress Scale (DASS-21)
Pain character: questionnaire 4 minutes McGill Pain questionnaire
Trial Locations
- Locations (1)
University Hospital Leuven
🇧🇪Leuven, Belgium