EFFECTIVENESS OF ADJUNCTIVE TRANSCRANIAL ALTERNATING CURRENT STIMULATION IN PATIENTS WITH SCHIZOPHRENIA FOR AUDITORY HALLUCINATIO
Not Applicable
- Conditions
- Health Condition 1: F20- Schizophrenia
- Registration Number
- CTRI/2023/07/055544
- Lead Sponsor
- Central Institute of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Diagnosis of schizophrenia using diagnostic criteria for research (DCR) of ICDâ??10 DCR (World Health Organization, 1993).
2. PSYRATS auditory hallucination subscale score on item frequency and duration >=2 each.
3. Right-handed.
4. Patients giving written informed consent.
Exclusion Criteria
1. Co-morbid neurological or any other psychiatric disorder.
2. History of substance abuse (except nicotine and caffeine).
3. History of epilepsy, significant head injury or any neurosurgical procedure.
4. Patients who have received electroconvulsive therapy in the past one month.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in scores of auditory hallucinations as recorded by Psychotic Symptom Rating Scale (PSYRATS) - Auditory Hallucination Sub-Scale, and Auditory hallucinations rating scale (AHRS)Timepoint: At completion of tACS sessions i.e., 1 week and at 5 weeks after the initiation of treatment
- Secondary Outcome Measures
Name Time Method Change in EEG gamma band (30-100 Hz) spectral power and synchronization from baseline to post-treatmentTimepoint: At completion of tACS sessions i.e., 1 week and at 5 weeks after the initiation of treatment