Positive Psychological Intervention for Parkinson's Disease Patients

Not Applicable

Completed

• Conditions: Parkinson

• Registration Number: NCT06832358
• Lead Sponsor: First Affiliated Hospital of Wenzhou Medical University

Brief Summary

This study aims to evaluate the impact of positive psychological intervention based on the PERMA model on Parkinson's disease patients by assessing their depression, quality of life, and related psychological indicators before and after intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-02-01
• Primary Completion: 2023-02-01
• Study Completion: 2023-04-01
• Status Verified: 2025-02
• Study First Submitted: 2025-02-12
• Study First Submitted QC: 2025-02-12
• Last Update Submitted: 2025-02-12
• Study First Posted: 2025-02-18
• Last Update Posted: 2025-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Subjects must meet the clinical diagnostic criteria for primary Parkinson's disease
• Subjects must not have a history of depression or other significant illnesses (e.g., stroke, coronary heart and tumor disease)
• Subjects should have clear consciousness, effective communication capabilities, and basic comprehension and reading skills to complete routine assessments
• The diagnosis of depression adhered to the ' Chinese Classification and Diagnostic Criteria for Mental Disorders ' (Revised Third Edition)
• Subjectsshould not have schizophrenia
• Subjects should not have substance abuse (alcohol, tobacco or other psychoactive substances)

Exclusion Criteria

• Subjects with significant mental or cognitive impairment that communication or completion of scale assessments
• Subjects exhibiting severe self-harm or suicidal tendencies
• Subjects with severe dysfunction of the heart, liver, kidney or other critical organs
• Subjects with contraindications for transcranial magnetic stimulation (such as cochlear implant, pacemaker, built-in pump, artificial metal heart valve, suspected metal in the eye or elevated intracranial pressure)
• Subjects with a history of epilepsy that is poorly controlled
• Subjects with Parkinson's disease who have undergone surgical treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the scores of Unified Parkinson's Disease Rating Scale(UPDRS)	after one month of intervention
the scores of Parkinson's Disease Quality of Life Scale(PDQ-39)	after one month of intervention
the scores of Hamilton Depression Scale(HAMD)	after one month of intervention
the scores of Hamilton Anxiety Scale(HAMA)	after one month of intervention
the scores of Connor-Davidson Resilience Scale(CD-RISC)	after one month of intervention
the scores of Pittsburgh Sleep Quality Index(PSQI)	after one month of intervention
the scores of Mini-Mental State Examination(MMSE)	after one month of intervention
the scores of Positive and Negative Affect Schedule (PANAS)	after one month of intervention
the Newcastle Nursing Satisfaction Scale score	after one month of intervention

Trial Locations

Locations (1)

The First Affiliated Hospital of Wenzhou Medical University; 🇨🇳 Wenzhou, China