The Effect of Exercise Training in Adult Patients with a Systemic Right Ventricle
Not yet recruiting
- Conditions
- congenital heart diseasetransposition of the great vessels1001039410007510
- Registration Number
- NL-OMON32565
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
systemic right ventricle
Exclusion Criteria
- Mental incapability to give informed consent
- Mental or physical incapability to participate in the exercise training program
- Exercise-induced arrhythmias
- Symptomatic myocardial ischemia
- Resting systolic blood pressure > 200 mmHg and/or diastolic blood pressure > 110 mmHg.
- NYHA class III or IV
- Severe aortic valve stenosis
- Non-cardiac co-morbidity that may affect exercise performance or that may aggravate by exercise (e.g. infection, renal failure)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is to determine whether exercise training improves<br /><br>maximal exercise capacity in adult patient with a systemic right ventricle.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary study parameters are to determine whether exercise training a).<br /><br>improves health related quality of life and b). decreases serum NT-proBNP<br /><br>levels in adult patients with adult a systemic right ventricle. </p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie exercise-induced improvements in systemic right ventricle function in adults with transposition of the great vessels?
How does structured exercise training compare to standard care in managing long-term outcomes for patients with a systemic right ventricle?
Are there specific biomarkers that predict response to exercise training in adults with congenital heart disease, particularly those with transposition of the great vessels?
What adverse events are associated with exercise training in patients with a systemic right ventricle, and how can they be managed effectively?
How do exercise training protocols for systemic right ventricle patients compare with those for other congenital heart disease subtypes like tetralogy of Fallot or atrial septal defect?