The comparison of effectiveness and safety of two different doses of aerosolized sedative dexmeditomidine to local anaesthetic agent lignocaine for conducting flexible fiberoptic bronchoscopy for purpose of diagnosis
Phase 4
- Conditions
- Health Condition 1: J00-J99- Diseases of the respiratory system
- Registration Number
- CTRI/2022/04/042057
- Lead Sponsor
- Ankita Kabi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American Society of Anesthesiologists (ASA) Physical Status I/ II patients
2. Age between 18 years to 65 years scheduled for an elective bronchoscopy procedure.
3. Patients willing to provide informed consent
Exclusion Criteria
1. Intubated patients
2. Inability to maintain oxygen saturation (SpO2 <90%)
3. History of bleeding diathesis
4. Known case of heart block
5. History of Anaphylaxis to any of the drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the cough reflexes scores during diagnostic awake flexible fiberoptic bronchoscopy in patients treated with 0.6 and 1 mcg/kg doses of dexmeditomidine and placebo as an adjuvant to 2% lignocaine. <br/ ><br>Timepoint: From introduction of fiberoptic bronchoscope into the nostril of the patient till 60 minutes <br/ ><br>
- Secondary Outcome Measures
Name Time Method