The effect of dexmedetomidine on reducing the incidence of cough after extubatio

Phase 3

Conditions: Tracheal Extubation.

Registration Number: IRCT20180416039326N19

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 540

Inclusion Criteria

Patients who are candidates for elective surgery
Age range is 18-60 years and with ASA class 1 and 2.
Patient consent to participate in the study

Exclusion Criteria

History of allergy to Alpha adrenergic drugs
Liver patients
Patients with a history of Bradycardia
Vascular problems
Hypotension
Vasodilator use
Hypovolemia
People who are at risk for increased intracranial pressure or intraocular pressure
Addicted people or Smokers
People with asthma
Patients with a history of airway infection or history of airway surgery.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic bBlood Pressure. Timepoint: Before Extubation and 1, 3, 5 and 10 minutes after extubation. Method of measurement: Barometer.;Diastolic blood pressure. Timepoint: Before Extubation and 1, 3, 5 and 10 minutes after extubation. Method of measurement: Barometer.;Pulse rate. Timepoint: Before Extubation and 1, 3, 5 and 10 minutes after extubation. Method of measurement: Pulse oximetry.;Oxygen saturation percentage. Timepoint: Before Extubation and 1, 3, 5 and 10 minutes after extubation. Method of measurement: Pulse oximetry.;Mean arterial pressure. Timepoint: Before Extubation and 1, 3, 5 and 10 minutes after extubation. Method of measurement: Barometer.;Cough. Timepoint: 1, 3, 5 and 10 minutes after the end of the extubation. Method of measurement: View.

Secondary Outcome Measures

Name	Time	Method
Duration of staying in recovery. Timepoint: Based on minutes from arrival to reaching the modified aldrete score of 9. Method of measurement: Information collection form.;Adverse airway response. Timepoint: During the time of staying in recovery. Method of measurement: Information collection form.;Hemodynamic complications. Timepoint: During the time of staying in recovery. Method of measurement: Information collection form.;Duration of extubation. Timepoint: Based on minutes from the time of discontinuing anesthetic to the time of extubation. Method of measurement: Information collection form.