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Clinical Trials/NCT05416619
NCT05416619
Completed
Not Applicable

Effects of Hand MOtor Rehabilitation Using a sEMG-biofeedback, After Stroke: a Longitudinal Pilot Study

IRCCS San Camillo, Venezia, Italy1 site in 1 country20 target enrollmentAugust 14, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
IRCCS San Camillo, Venezia, Italy
Enrollment
20
Locations
1
Primary Endpoint
Fugl-Meyer Upper Extremity
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Stroke is the first cause of disability worldwide. The motor impairment of the hand is one of the most common sequelae in patients after stroke. Indeed, approximately 60% of patients with diagnosis of stroke suffers from hand sensorimotor impairment. In the last years, new approaches in neurorehabilitation field has been permitted to enhance hand motor recovery. Wearable devices permit to apply sensors to the patient's body for monitoring the kinematic and dynamic characteristics of patient's motion. Moreover, wearable sensors combined with electrodes detecting muscle activation (i.e. surface electromyography - sEMG) permit to provide biofeedback to the patient to improve motor recovery.

Detailed Description

The aim of the study is to investigate the effect of using REMO® (Morecognition srl, Turin, Italy) device in hand motor rehabilitation. The device REMO® is an armband composed by 8 bipolar electrodes able to record and process the electromyography of forearm muscles. The patterns of muscle activations are classified and used to perform sEMG-biofeedback exercises in stroke rehabilitation training. The device is developed by clinicians of IRCCS San Camillo Hospital and Morecognition Srl. A total of 20 patients with first diagnosis of stroke and with no other neurological diagnosis or severe cognitive impairment has been enrolled. The patients are tested with REMO® and if they are able to control at least one movements, they are enrolled in the longitudinal pilot study. The treatment consists in 15 sessions, 1hour/day, for 5 days/week, for 3 weeks. The patients are clinically evaluated before and after the REMO® treatment to define clinical effect of the sEMG-biofeedback training.

Registry
clinicaltrials.gov
Start Date
August 14, 2017
End Date
February 27, 2019
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
IRCCS San Camillo, Venezia, Italy
Responsible Party
Principal Investigator
Principal Investigator

Andrea Turolla

Principal Investigator

IRCCS San Camillo, Venezia, Italy

Eligibility Criteria

Inclusion Criteria

  • Single ischemic or haemorrhagic stroke
  • able to control at least 1 movement with REMO (i.e. able to cross the pre-defined empirical threshold (10%) of the ratio between the maximum voluntary contraction (MVC) of the movement and the EMG recording during baseline (i.e. rest position)

Exclusion Criteria

  • Untreated epilepsy;
  • Major depressive disorder;
  • Fractures;
  • Traumatic Brain Injury;
  • Severe Ideomotor Apraxia;
  • Severe Neglect;
  • Severe impairment of verbal comprehension.

Outcomes

Primary Outcomes

Fugl-Meyer Upper Extremity

Time Frame: Change from baseline, at 3 weeks (15 sessions).

Fugl-Meyer Upper Extremity is a stroke-specific scale which assesses the upper limb motor functioning in patients with post-stroke hemiplegia. There are 3 values: 0 (severe impairment), 1 (moderate impairment), 2 (preserved function). The minimum value is 0 points, which corresponds to upper limb hemiplegia. The maximum value is 66 points, which corresponds to normal motor performance.

Secondary Outcomes

  • Fugl-Meyer - sensation(Change from baseline, at 3 weeks (15 sessions).)
  • Fugl-Meyer - pain and Range of Motion(Change from baseline, at 3 weeks (15 sessions).)
  • Box and Blocks Test(Change from baseline, at 3 weeks (15 sessions).)
  • Reaching Performance Scale(Change from baseline, at 3 weeks (15 sessions).)
  • Modified Ashworth Scale(Change from baseline, at 3 weeks (15 sessions).)
  • Nine Hole Pegboard Test(Change from baseline, at 3 weeks (15 sessions).)
  • Functional Independence Measure(Change from baseline, at 3 weeks (15 sessions).)
  • Number of movements controlled by REMO® device(Change from baseline, at 3 weeks (15 sessions).)

Study Sites (1)

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