Effect of Alfentanil and Remifentanil on QT Interval
Phase 2
- Conditions
- QT Prolongation.Electrocardiogram [ECG][EKG]R 94.3
- Registration Number
- IRCT2014020816524N1
- Lead Sponsor
- Vice Chancellor for Research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients with physical status class I -II, based on the classification of the American Society of Anesthesiologists (ASA) and the age up to50 years undergoing septoplasty. Exclusion criteria: the use of any effective drug on QT interval in 14 days before surgery (TCA); beta antagonist, anti-arrhythmic, the calcium channel blocker) ; QTc more than 440 m/s; The existence of branches blocks, arrhythmia (preexitation syndrome) ; Structural heart disease.; electrolyte imbalance; hyper or hypothyroid patients 7. Extreme Obesity BMI 30 >; Diabetic neuropathy; Any non- sinus rhythm in EKG; A history of sensitivity to propofol, egg and soy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method QT interval. Timepoint: Prioperative /Six times. Method of measurement: EKG.
- Secondary Outcome Measures
Name Time Method Heart Rate Monitoring. Timepoint: Six Times Perioperative. Method of measurement: EKG.