Comparing the effect of of Remifentanil and Apotel on postoperative pain in Total knee arthroplasty patients
Phase 2
Recruiting
- Conditions
- Knee joint arthritis.Pain in jointM25.5
- Registration Number
- IRCT20220812055663N1
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
All candidate patients for knee joint replacement surgery referred to Amir-al-Momenin Hospital in Arak
Patients in the age range of 18 to 60 years
All patients undergo knee joint replacement by arthroplasty method
Patients have informed consent
Exclusion Criteria
All patients whose duration of surgery is more than 150 minutes
All patients in whom spinal anesthesia fails and have to undergo general anesthesia
Patients with ASA class 3 and 4
sensitivity/allergy to local anesthetics, Apotel and opioids
The patient has an underlying heart, lung, liver, kidney, etc. disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average post-operational Visual Analogue Scale(VAS) in patients. Timepoint: 2, 4, 8,12 and 24 hours after surgery. Method of measurement: Questionnaire.;Average duration of postoperative analgesia. Timepoint: Up to 24 hours after the operation. Method of measurement: Questionnaire.;Average opioid consumption after surgery. Timepoint: 24 hours after the operation. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method Average mean arterial pressure of patients in recovery. Timepoint: Duration of observation in recovery. Method of measurement: Monitor.;Average pulse rate of patients in recovery. Timepoint: Duration of observation in recovery. Method of measurement: Monitor.;Average SPO2 of patients in recovery. Timepoint: Duration of observation in recovery. Method of measurement: Monitor.