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Clinical Trials/NCT04829526
NCT04829526
Recruiting
Not Applicable

Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome (FOCUS on GBS)

University Hospital, Basel, Switzerland1 site in 1 country100 target enrollmentMarch 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Guillain-Barre Syndrome (GBS)
Sponsor
University Hospital, Basel, Switzerland
Enrollment
100
Locations
1
Primary Endpoint
frequency of GBS
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The aim of this retrospective observational single-center cohort study is to gain a deeper understanding regarding the frequency, the clinical and electrophysiologic characteristics (e.g., the diagnostic work up), complications, treatment regimes, and their associations with specific courses of disease and outcomes in adult patients with the suspected or proven diagnosis of GBS.

Detailed Description

Guillain Barré Syndrome (GBS) is a rare and life-threatening neurological emergency. The aim of this retrospective study including adult GBS patients from the last 15 years treated at the University Hospital of Basel is to assess data regarding diagnostic workup, treatment, clinical course including complications and outcomes.

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
July 2026
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Basel, Switzerland
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • suspected diagnosis of GBS, who have been treated at the University Hospital of Basel from 01.01.2005-28.02.2021

Exclusion Criteria

  • Patients with documented refusal of the general consent.

Outcomes

Primary Outcomes

frequency of GBS

Time Frame: one time retrospective assessment at baseline

frequency of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

clinical characteristics of GBS

Time Frame: one time retrospective assessment at baseline

clinical characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

electrophysiologic characteristics of GBS

Time Frame: one time retrospective assessment at baseline

electrophysiologic characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

complications of GBS

Time Frame: one time retrospective assessment at baseline

complications of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

treatment regimes of GBS

Time Frame: one time retrospective assessment at baseline

treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

outcomes of GBS

Time Frame: one time retrospective assessment at baseline

treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)

Study Sites (1)

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