Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome (FOCUS on GBS)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 2
- Primary Endpoint
- frequency of GBS
Study Overview
Brief Summary
The aim of this retrospective observational single-center cohort study is to gain a deeper understanding regarding the frequency, the clinical and electrophysiologic characteristics (e.g., the diagnostic work up), complications, treatment regimes, and their associations with specific courses of disease and outcomes in adult patients with the suspected or proven diagnosis of GBS.
Detailed Description
Guillain Barré Syndrome (GBS) is a rare and life-threatening neurological emergency. The aim of this retrospective study including adult GBS patients from the last 15 years treated at the University Hospital of Basel is to assess data regarding diagnostic workup, treatment, clinical course including complications and outcomes.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •suspected diagnosis of GBS, who have been treated at the University Hospital of Basel from 01.01.2005-28.02.2021
Exclusion Criteria
- •Patients with documented refusal of the general consent.
Outcomes
Primary Outcomes
frequency of GBS
Time Frame: one time retrospective assessment at baseline
frequency of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
clinical characteristics of GBS
Time Frame: one time retrospective assessment at baseline
clinical characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
electrophysiologic characteristics of GBS
Time Frame: one time retrospective assessment at baseline
electrophysiologic characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
complications of GBS
Time Frame: one time retrospective assessment at baseline
complications of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
treatment regimes of GBS
Time Frame: one time retrospective assessment at baseline
treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
outcomes of GBS
Time Frame: one time retrospective assessment at baseline
treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)
Secondary Outcomes
No secondary outcomes reported