Comparison Between Partial Nephrectomy and Ablation for Renal Tumor

Not Applicable

• Conditions: Renal Cell Carcinoma
• Interventions: Procedure: microwave ablation; Procedure: Partial Nephrectomy

• Registration Number: NCT03094949
• Lead Sponsor: Chinese PLA General Hospital

Brief Summary

The therapeutic effectiveness of ultrasound guided cooled-probe microwave ablation and laparoscopic partial nephrectomy on T1a renal cell carcinoma is compared to find a better approach for renal tumor.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-01
• Status Verified: 2017-03
• Study First Submitted: 2017-03-01
• Study First Submitted QC: 2017-03-23
• Last Update Submitted: 2017-03-23
• Study First Posted: 2017-03-29
• Last Update Posted: 2017-03-29
• Primary Completion: 2017-07-01
• Study Completion: 2017-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients with the RCC of ≤4 cm maximum diameter were included in the study.

Exclusion Criteria

• Patients having RCCs with vascular invasion, extrarenal spread or with benign renal tumors were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
microwave ablation	microwave ablation	a kind of minimally invasive therapy by using microwave device for renal tumors
Partial Nephrectomy	Partial Nephrectomy	a kind of operation for renal tumor

Primary Outcome Measures

Name	Time	Method
overall survival	5 years	using log-rank test

Secondary Outcome Measures

Name	Time	Method
local tumor progress(new lesion found adjacent to ablation zone)	5 years	using log-rank test
rate of extrarenal metastasis(new lesion found outside of treated kidney)	5 years	using log-rank test
number of patients with side-effect and major complications	1 month	using chi-square test
rate of intrarenal metastasis(new lesion found in the treated kidney, but not adjacent to ablation zone)	5 years	using log-rank test

Trial Locations

Locations (1)

Chinese PLA General Hospital; 🇨🇳 Beijing, Beijing, China