Multimodal PREhabilitation and its impact in sarCopenic patients inminimally invAsive coloREctal surgery - a prospective, randomizedcontrolled trial

Not Applicable

Recruiting

• Conditions: C18.9; K57.3; K63.5; M62.5; Colon, unspecified; Diverticular disease of large intestine without perforation or abscess; Polyp of colon; Muscle wasting and atrophy, not elsewhere classified

• Registration Number: DRKS00032812
• Lead Sponsor: Abteilung für Allgemein - und Viszeralchirurgie, KH der Barmherzigen Brüder Salzburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Elective, minimally inverse colorectal resection for:
- recurrent diverticulitis
- Endoscopically not resectable colorectal polyp
- Colorectal cancer UICC I-III
Written informed consent
Appropriate language skills to follow the study protocol

Exclusion Criteria

Acute surgery for perforation or ileus
Open surgery
Illness that makes participation in the planned interventions impossible
Pregnancy
Rejection of study participation
Missing legal capacity for written informed consent
Palliative resections for UICC IV colorectal cancer

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
6-minute-walk-test on postoperative day 28

Secondary Outcome Measures

Name	Time	Method
1. postoperative Complication-rate (Clavien-Dindo)<br>2. Length of stay<br>3. length of ICU stay<br>4. Changes in body impedance analysis 28th day post-op compared to baseline<br>5. Grip strength 28th day post-OP compared to baseline<br>6. Depression- and fear-score (PHQ-9 and GAD-7) as well as PHQ stress-model 28th day post operative compared to baseline