Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow

Not Applicable

• Conditions: Accident Caused by Snow Avalanche
• Interventions: Other: extreme hypercapnia induced by ventilation insufficiency

• Registration Number: NCT05262894
• Lead Sponsor: Czech Technical University in Prague

Brief Summary

The study is aimed at investigation of respiratory gases propagation in snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow.

Detailed Description

The study is aimed at investigation of respiratory gases (oxygen and carbon dioxide) propagation in the simulated avalanche snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow. A special apparatus was created for sampling and measurement of gas concentrations and to assure stable geometry of the experiment required for data evaluation.

Study Timeline

• Status Verified: 2022-02
• Study Start: 2022-02-07
• Study First Submitted: 2022-02-21
• Study First Submitted QC: 2022-03-01
• Last Update Submitted: 2022-03-01
• Study First Posted: 2022-03-02
• Last Update Posted: 2022-03-02
• Primary Completion: 2025-05-31
• Study Completion: 2025-05-31

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• healthy and fit volunteers, classified as The American Society of Anesthesiologists class I
• without a smoking history

Exclusion Criteria

• Tiffeneau Index less than 0.70
• any cardiovascular or respiratory condition

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Breathing in the snow	extreme hypercapnia induced by ventilation insufficiency	Breathing in the snow using a specially designed apparatus and measuring the respiratory gases distribution in snow.

Primary Outcome Measures

Name	Time	Method
The length of breathing	Continuously within up to 20 minute interval from the beginning of the breathing experiment	Time to termination of the breathing experiment due to the decision of the tested subject, or determined by high end-tidal carbon dioxide value or by the order by the clinician assessing the health status of the subjects.

Trial Locations

Locations (1)

Czech Technical University, Faculty of Biomedical Engineering; 🇨🇿 Kladno, Czechia