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Clinical Trials/NCT07637331
NCT07637331RecruitingNot Applicable

The Effect of Respiratory Muscle Training on Cognitive Performance

Indiana University1 site in 1 country32 target enrollmentStarted: March 27, 2026Last updated:
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
32
Locations
1

Study Overview

Brief Summary

Determine if exercise training for the respiratory muscles improves cognitive performance during periods when breathing against a resistance.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Triple (Participant, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 40 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • 18-40 years old
  • Body mass index <30 kg/m2
  • Naïve to IMT
  • >75% of predicted forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC) (FEV1/FVC)
  • Access to smart phone or tablet with internet

Exclusion Criteria

  • Diagnosed:
  • Cardiovascular disease
  • Respiratory disease (including asthma)
  • Metabolic disease
  • Currently pregnant
  • Unable to adhere to the IMT protocol
  • Answering 'yes' to any of the questions on page one of the PAR-Q+
  • Abnormal cognition assessed via the Montreal Cognitive Assessment (score of 25 or less)
  • Self-reported color blindness
  • Significant acute or chronic medical, neurologic, or illness in the participant that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability of the participant to complete the study, and/or compromise the objectives of the study

Arms & Interventions

Active IMT

Experimental

Inspiratory muscle training

Intervention: Inspiratory muscle training (Device)

Sham IMT

Sham Comparator

Sham inspiratory muscle training

Intervention: Inspiratory muscle training (Device)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Blair D. Johnson, PhD

Associate Professor Kinesiology

Indiana University

Study Sites (1)

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