IRCT20190305042939N2招募中3 期
Evaluation of the effects of curcumin supplementation on oxidative stress indices in patients treated with cisplatin: a double-blind, placebo-controlled randomized clinical trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Patients with malignancy who receive cisplatin for the first time in their treatment regimens
- •GFR higher than 60 mL/min based on CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
- •The patient be able to receive curcumin orally
排除标准
- •Patients with active infection or symptoms of sepsis
- •Patients who have received nephrotoxic drugs such as aminoglycoside, amphotericin, vancomycin, colistin, media contrast, calcineurin inhibitors or Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for the past 72 hours
- •Patients who have a history of taking cisplatin
- •Patients who may experience complications or allergic reactions to curcumin during treatment
- •Patients who had a history of acute kidney injury ( AKI ) before entering the study
- •The patient's unwillingness to cooperate during the research
- •Patients with bilirubin above 2 mg / dl or liver enzymes above 2.5 times the normal level
研究者
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