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Clinical Trials/NCT02902263
NCT02902263
Completed
Not Applicable

Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis in France Comté

Centre Hospitalier Universitaire de Besancon1 site in 1 country79 target enrollmentJanuary 2014
ConditionsIschemic Stroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ischemic Stroke
Sponsor
Centre Hospitalier Universitaire de Besancon
Enrollment
79
Locations
1
Primary Endpoint
Patient neurological status assessed by NIHSS score during transfer to NVU
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset.

In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation.

The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before.

It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France).

Detailed Description

Stroke is a major health problem with increasing incidence. It represents the leading cause of disability and the third cause of death in France. There are two main types of stroke: ischemic (80%) or hemorrhagic (20%). Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset. In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation. The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before. It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France). Evaluation of neurological status was made with the Glasgow score (GCS) and National Institute of Health Stroke Score (NIHSS). The respiratory (SpO2; needs O2) and hemodynamic status (arterial blood pressure, heart rate) were assessed as well as the need for medical resuscitation at different times of the transport (thrombolysis, transfer, arrival at the Regional University Hospital Centre).

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
January 2016
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient with ischaemic stroke
  • Emergency department admission between 01/01/2012 and 12/31/2013
  • Telemedicine stroke consult
  • Thrombolysis therapy
  • Patient transfered to NVU after thrombolysis initiation
  • Transfer staffed by a qualified physician

Exclusion Criteria

  • Transfer non staffed by a qualified physician

Outcomes

Primary Outcomes

Patient neurological status assessed by NIHSS score during transfer to NVU

Time Frame: one day

Patient neurological status assessed by Glasgow score during transfer to NVU

Time Frame: one day

Secondary Outcomes

  • Patient respiratory status assessed by oxygen saturation(one day)
  • Patient hemodynamic status assessed by systolic and diastolic pressure(one day)

Study Sites (1)

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