Reduction of In-hospital Delays in Stroke Thrombolysis: SITS-WATCH
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- SITS International
- Enrollment
- 3000
- Locations
- 1
- Primary Endpoint
- Absolute DNT reduction of at least 20 minutes or at least 20% change in SITS-WATCH centers that completed the whole study period
- Last Updated
- 13 years ago
Overview
Brief Summary
In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). SITS-WATCH aims to reduce median DNT in participating centres.
Detailed Description
In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). Of the two, DNT can be directly influenced within the hospital by stream-lining of acute stroke care. The aim of our study is to reduce in-hospital delays (DNT) in self-selecting centers recruiting patients into the the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) , comprising currently more than 80 000 patients from 1338 centers. Current median of DNT in all SITS centers is 65 minutes (compared with 20 minutes in Helsinki Univer-sity Central Hospital). An itemized detailed questionnaire, including all factors known to influence DNT, has been sent to all SITS centers to identify the reasons for long in-hospital delays. Based on the replies, we have prepared a list of interventions that can be considered by individual SITS centers in order to reduce DNT with interventions that are in line with national legislation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All consecutive patients with acute ischemic stroke registered in SITS registry.
Exclusion Criteria
- •Centers not inputing patient data into SITS registry. Patients with missing DNT data.
Outcomes
Primary Outcomes
Absolute DNT reduction of at least 20 minutes or at least 20% change in SITS-WATCH centers that completed the whole study period
Time Frame: January 2013-December 2014
DNT will be evaluated at regular intervals (twice a year).
Secondary Outcomes
- Significantly larger reduction of DNT in SITS-WATCH centers compared with non-SITS-WATCH centers in SITS.(2014-2015)