Reduction of In-hospital Delays in Stroke Thrombolysis: SITS-WATCH
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 3,000
- 试验地点
- 2
- 主要终点
- Absolute DNT reduction of at least 20 minutes or at least 20% change in SITS-WATCH centers that completed the whole study period
研究概览
简要总结
In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). SITS-WATCH aims to reduce median DNT in participating centres.
详细描述
In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). Of the two, DNT can be directly influenced within the hospital by stream-lining of acute stroke care. The aim of our study is to reduce in-hospital delays (DNT) in self-selecting centers recruiting patients into the the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) , comprising currently more than 80 000 patients from 1338 centers. Current median of DNT in all SITS centers is 65 minutes (compared with 20 minutes in Helsinki Univer-sity Central Hospital). An itemized detailed questionnaire, including all factors known to influence DNT, has been sent to all SITS centers to identify the reasons for long in-hospital delays. Based on the replies, we have prepared a list of interventions that can be considered by individual SITS centers in order to reduce DNT with interventions that are in line with national legislation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All consecutive patients with acute ischemic stroke registered in SITS registry.
排除标准
- •Centers not inputing patient data into SITS registry. Patients with missing DNT data.
研究组 & 干预措施
Intervention group (SITS-WATCH centers)
15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.
干预措施: Reduction of DTN (Other)
Control group (non SITS-WATCH centers in SITS registry)
Centres that do not use 15-item list of suggested interventions aiming to reduce DNT.
结局指标
主要结局
Absolute DNT reduction of at least 20 minutes or at least 20% change in SITS-WATCH centers that completed the whole study period
时间窗: January 2013-December 2014
DNT will be evaluated at regular intervals (twice a year).
次要结局
- Significantly larger reduction of DNT in SITS-WATCH centers compared with non-SITS-WATCH centers in SITS.(2014-2015)