MedPath

Comparison of therapeutic effects of topical Isotretinoin %0.05 and Clindamycine %1 in the treatment of acne vulgaris

Phase 2
Conditions
mild to moderate acne vulgaris.
Acne vulgaris
Registration Number
IRCT201105032581N2
Lead Sponsor
Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

patients with mild to moderate acne between 11 to 30 years old; patients who have at most 20 inflammatory lesion (papule, pustule) in one side of face and don't have more than 3 nodule or cyst in the same side; tendency to intend in study. Exclusion criteria: pregnant and lactating women; patients who have used topical anti acne drugs in the recent month; patients who have used oral anti acne drugs in past 2 months; having any other facial skin disease other than acne; having sever nodulocystic acne; consumption of acne inducing drugs such as lithium, oral steroid, vit B12, brom and iodide drugs; patients who have more than 20 inflammatory lesion (papule, pustule) in one side of face and have more than 3 nodule or cyst in the same side.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity. Timepoint: every 30 days. Method of measurement: History and clinical examination.
Secondary Outcome Measures
NameTimeMethod
Pustules. Timepoint: every 30 days. Method of measurement: clinical examination.;Total acne lesions. Timepoint: every 30 days. Method of measurement: clinical examination.;Index of acne severity. Timepoint: every 30 days. Method of measurement: clinical examination, statistical measurment.;Patient satisfaction. Timepoint: every 30 days. Method of measurement: Questionnare.;Comedones. Timepoint: every 30 days. Method of measurement: clinical examination.
© Copyright 2025. All Rights Reserved by MedPath