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Cone-beam computed tomography guided percutaneous cryoablation approach of bone metastases of endocrine tumors - BONEMET-CRYO: bone metastases - cryoablation

Instituto de Radiologia do Hospital das Clínicas / Faculdade de Medicina da Universidade de São Paulo0 个研究点开始时间: 2018年7月3日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•patients with bone metastases diagnosis evidenced by imaging exams (CT, MRI and/or PET-CT) and secondary to: papillary, folicular or medullary thyroid cancer; adrenal carcinoma; neuroendocrine carcinomas; metastatic bone lesions associated with: pain; risk of fracture; risk of spinal cord compression; hypercalcemia; age over or equal 18 years old; performance status (ECOG) of 0, 1, 2 or 3; life expectation over one month; patients must present pain symptoms from bone metastases and / or localized in a region of imminent risk of instability / fracture that may progress to neurological complication (for example, vertebral metastases) or functional impairment (for example, acetabular metastases); all patients must present diagnosis confirmation from metastases biopsy; the same treated patients can be treated again if they present new lesions during the study; all patients must be evaluated for treatment indication by a multidisciplinary team; the metastatic lesions may be located at the axial skeleton, costal arches, shoulder or pelvic girdle; each bone metastases assigned for treatment must be biopsy-proven and / or presenting elevation of thyroglobulin or calcitonin levels in the needle wash, if thyroid carcinoma is present; all patients must present five symptomatic bone metastases maximum; all selected metastases must have 7.0 cm diameter maximum;

发起方

Instituto de Radiologia do Hospital das Clínicas / Faculdade de Medicina da Universidade de São Paulo