A clinical study to compare pain relief for block performed before and after surgery in patients having surgeries in the jaw

Not yet recruiting

• Conditions: Fracture of skull and facial bones,

• Registration Number: CTRI/2019/11/021902
• Lead Sponsor: SRM Medical College Hospital

Brief Summary

Patients posted for mandibular fracture fixation surgeries will be included in the study. The patients will be randomly divided into two groups. Group A will receive mandibular nerve block after anaesthesia induction and endotracheal intubation and prior to surgical incision. Group B patients will receive mandibular nerve block at the end of surgery. Both the blocks will be performed with the aid of ultrasound and using Ropivacaine 0.5% 10ml.

The general anaesthesia will be standardized in both the groups. At the end of sugery, the patient will be put on patient controlled analgesia (PCA) using morphine with bolus of 1mg and lockout interval of 10 minutes.

The duration of postoperative analgesia, consumption of morphine in PCA and haemodynamic parameters will be obseved in both the groups and compared. Descriptive statics ( mean , standard deviation, and frequency ) will be included . to compare quantitive data , chi-square test was used . the results will be expressed in 95% confidence interval . a valve of p<0.05 will be considered to be statistically significant.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-04-11
• Study Start: 2019-11-18

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients with ASA Physical Status I and II posted for fractures of mandible.

Exclusion Criteria

• All patients with ASA Physical Status III and above 2.
• Patients who refuse to participate in the study 3.
• Patients who are allergic to amide local anaesthetics 4.
• Patients who are pregnant 5.
• Patients with chronic cardiac, renal or hepatic condition 6.
• Patients with coagulation abnormalities.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of postoperative analgesia	within 24 hours of surgery

Secondary Outcome Measures

Name	Time	Method
Haemodynamic parameters	The heart rate,and blood pressure intraoperatively will be observed.
Morphine consumption	The total consumption of morphine in the first 24 hours in PCA pump will be recorded

Trial Locations

Locations (1)

SRM Medical College Hospital; 🇮🇳 Kancheepuram, TAMIL NADU, India

SRM Medical College Hospital

🇮🇳Kancheepuram, TAMIL NADU, India

Rajagopalan Venkatraman

Principal investigator

9894581455

drvenkat94@gmail.com