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Digital Health for Caregivers Emotional and Self-management Support

Completed
Conditions
Mood Disturbance
Emotional Adjustment
Interventions
Behavioral: mHealth solution based on emotional and behavioral change techniques
Registration Number
NCT04812665
Lead Sponsor
Adhera Health, Inc.
Brief Summary

This feasibility study builds upon mental health and technology acceptance theoretical frameworks. It seeks to examine potentials of a novel mobile Health (mHealth) solution based on emotional and behavioral change techniques, to provide emotional and self-management tailored support to caregivers of children undergoing Growth Hormone treatment (GHt).

Detailed Description

This feasibility study builds upon mental health and technology acceptance theoretical frameworks. It seeks to examine potentials of a novel mobile Health (mHealth) solution based on emotional and behavioral change techniques, to provide emotional and self-management tailored support to caregivers of children undergoing Growth Hormone treatment (GHt).

Primary Objectives:

* To gather qualitative information enabling to better understand individualized experiences of caregiving children undergoing GHt and perceived barriers/facilitators for adoption of the mHealth solution.

* To assess positive mood states of caregivers of GHt patients as an indicator of emotional wellbeing related to the use of the mHealth solution.

Secondary Objectives:

To explore whether the mHealth solution applied to caregivers of children undergoing GHt might affect:

* Broader emotion-related parameters: Distress (emotional disturbance), self-efficacy (perceived own capability of managing stress), and general psychological wellbeing of caregivers.

* Perceived Health-related quality of life (HRQoL) of children (evaluated from the caregivers' perspective).

* Behavioral parameters: Usability / engagement with the mHealth solution and children's adherence to treatment measured by Easypod-Connect.

* Growth parameters: height of the child.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
65
Inclusion Criteria
  • Adherence to GHt monitored in the last month prior enrollment indicates a ratio less than 85%.
  • Legal guardian of children who receive GHt in accordance with approved indications in Spain.
  • Explicit agreement on data sharing regarding adherence to GHt gathered through the Easypod Connect.
  • Participants must be able to interact with a smart phone and willing to install the mHealth solution of the study in their smart phone.
  • Participants must sign the specific informed consent form for the study.
Exclusion Criteria
  • Candidates without an smart phone or not being able to interact with it.
  • Only one legal guardian per child can participate in the study.
  • Participants of SS1 will not take part in SS2.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Quantitative sub-study (SS2)mHealth solution based on emotional and behavioral change techniquesA different group of caregivers (n = 55) will engage with the mHealth solution during 3 months. As elaborated in the following sections, a quantitative approach will be adopted to assess different emotional, behavioral and growth parameters before and after engaging with the mHealth solution (pre-post design).
Qualitative sub-study (SS1)mHealth solution based on emotional and behavioral change techniquesOne group of caregivers (n = 10) will engage with the mHealth solution during 1 month. Subsequently, an individual semi-structured interview with each of the participants will proceed to gather user experience qualitative information.
Primary Outcome Measures
NameTimeMethod
Sub-study 1: Psychological burdens experienced as caregivers of children receiving GHt and barriers/facilitators for adopting the mHealth solution1 Month

A semi-structured interview based on a mental health and technology acceptance theoretical framework has been specifically designed for this purpose

Sub-study 2: Changes on caregiver's positive mood3 Months

Positive subscale of the Positive and Negative Affect Scale (PANAS). Scores can range from 10-50 for both the Positive and Negative Affect with the lower scores representing lower levels of Positive/Negative Affect and higher scores representing higher levels of Positive/Negative Affect.

Secondary Outcome Measures
NameTimeMethod
Emotional outcome: Changes on caregiver's perceived self-efficacy3 Months

Perceived self-efficacy assessment with the General Self-Efficacy Scale (GSE), the total score ranges between 10 and 40, with a higher score indicating more self-efficacy.

Emotional outcome: Changes on caregiver's general wellbeing3 Months

Assessed with the short form of the Mental Health Continuum - short form questionnaire (MHC-SF). Total sum scores on the MHC-SF can range from 0 to 70, with higher scores indicating higher levels of well-being.

Health-related Quality of Life (HrQoL): Changes on child's HRQoL3 Months

Child HRQoL assessment with Quality of Life in Short Statured Youth (QoLISSY) questionnaire answered by the caregiver as a proxy. This version has 47 items with a 5-point likert scale each. Total score is linearly transformed into 0 to 100 scores with higher values representing higher HRQOL.

Growth parameter: height6 Months

Height is a crucial indicator of the growth of children under Growth Hormone therapy. Measures from 6 month before starting the study to the end of the study will be obtained from Patient's Electronic Health Record.

Behavioral outcome: Usability3 Months

mHealth solution usability assessed with the System Usability Scale (SUS) questionnaire. SUS can range between 0 and 100 scores, with higher values representing higher usability.

Behavioral outcome: Treatment adherence3 Months

Adherence to the Growth Hormone treatment (GHt) will be measured with the data collected by the Easypod Connect device.

Emotional outcome: Changes on caregiver's distress3 Months

Distress assessed with the depression, anxiety, and stress scale (DASS-21). DASS-21 is a self-report questionnaire consisting of 21 items, 7 items per subscale: depression, anxiety and stress. Patients are asked to score every item on a scale from 0 (did not apply to me at all) to 3 (applied to me very much). Sum scores are computed by adding up the scores on the items per (sub)scale and multiplying them by a factor 2. Sum scores for the total DASS-total scale thus range between 0 and 120, and those for each of the subscales may range between 0 and 42. Cut-off scores of 60 and 21 are used for the total DASS score and for the subscales respectively. Scores ≥60 (for DASS-total) and ≥21 (for the depression subscale) are labeled as "high" or "severe".

Trial Locations

Locations (1)

Hospital Universitario Miguel Servet

🇪🇸

Zaragoza, Aragón, Spain

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