Liver Fibrosis Evaluation Using Ultrasound Shear Wave Imaging
- Conditions
- Liver Fibrosis
- Registration Number
- NCT03637959
- Lead Sponsor
- Mayo Clinic
- Brief Summary
The Researchers are trying to assess the effectiveness of a new ultrasound technique for non-invasive evaluation of liver fibrosis.
- Detailed Description
Utilizing vibrating transducer, receiver and speaker in differing sequences, while collecting ultrasound liver tissue elastography measurements during participant breath holds. Participants fast for a minimum of four hours and are positioned lying on left side with knees slightly bent.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 270
- Healthy volunteers or patients who are scheduled for clinically indicated liver MRE for fibrosis staging.
- Age 18 to 80.
- Subjects lacking capacity to consent
- Subjects with unreliable ultrasound or MRE measurements.
- Pregnant women.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Liver Stiffness Measured by MRE Baseline, approximately 1 day Liver stiffness measured by standard of care Magnetic Resonance Elastography reported in Kilopascals (kPa) (used as a benchmark reference in this study).
Liver Stiffness Measured by Mechanical Vibrations With Ultrasound Shear Wave Imaging Baseline, approximately 1 day Liver stiffness measured by Mechanical Vibrations with Ultrasound Shear Wave Imaging reported in kilopascal (kPa).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Mayo Clinic🇺🇸Rochester, Minnesota, United States