Liver Fibrosis Evaluation Using Ultrasound Shear Wave Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 270
- 试验地点
- 2
- 主要终点
- Liver Stiffness Measured by MRE
研究概览
简要总结
The Researchers are trying to assess the effectiveness of a new ultrasound technique for non-invasive evaluation of liver fibrosis.
详细描述
Utilizing vibrating transducer, receiver and speaker in differing sequences, while collecting ultrasound liver tissue elastography measurements during participant breath holds. Participants fast for a minimum of four hours and are positioned lying on left side with knees slightly bent.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers or patients who are scheduled for clinically indicated liver MRE for fibrosis staging.
- •Age 18 to 80.
排除标准
- •Subjects lacking capacity to consent
- •Subjects with unreliable ultrasound or MRE measurements.
- •Pregnant women.
结局指标
主要结局
Liver Stiffness Measured by MRE
时间窗: Baseline, approximately 1 day
Liver stiffness measured by standard of care Magnetic Resonance Elastography reported in Kilopascals (kPa) (used as a benchmark reference in this study).
Liver Stiffness Measured by Mechanical Vibrations With Ultrasound Shear Wave Imaging
时间窗: Baseline, approximately 1 day
Liver stiffness measured by Mechanical Vibrations with Ultrasound Shear Wave Imaging reported in kilopascal (kPa).
次要结局
未报告次要终点