Caffeine and Sodium Citrate Ingestion

Not Applicable

Completed

• Conditions: Dietary Supplements; Lactic Acid/Metabolism; Physical Education and Training/Methods; Wheelchairs; Heart Rate/Drug Effects

• Registration Number: NCT01591226
• Lead Sponsor: Swiss Paraplegic Research, Nottwil

Brief Summary

A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.

The aim of the study is to investigate whether caffeine or sodium citrate ingestion could enhance performance in spinal cord injured wheelchair athletes. It is a double blind, placebo controlled and randomized study.

Detailed Description

The athletes have to complete four 1500m tests on a training roller. Before each treatment they get different supplementations. Once they get sodium citrate and a placebo, once caffeine and a placebo, once sodium citrate and caffeine and for the fourth treatment they get twice a placebo. Two hours after starting with the supplementation they have to complete the 1500m as fast as possible. Time to complete 1500m, blood pH, plasma bicarbonate, sodium concentration, heart rate, oxygen consumption, blood lactate concentration and rate of perceived exertion (RPE) were measured.

Study Timeline

• Study Start: 2012-02
• Study First Submitted: 2012-04-03
• Study First Submitted QC: 2012-05-01
• Study First Posted: 2012-05-03
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-21
• Last Update Posted: 2016-11-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• wheelchair athletes
• national team
• category T53 and T54

Exclusion Criteria

• medicated
• pregnant (for women)
• cardiovascular and respiratory diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
Time	3 weeks	Time to complete 1500m

Secondary Outcome Measures

Name	Time	Method
blood pH, sodium concentration and plasma bicarbonate	during the 3 weeks of study phase	1min before starting with the ingestion of the fluid, immediately before starting the warm up, just immediately before starting the 1500m test.
Lactate Concentration	during the 3 weeks study phase	1min before starting the warm up, 15s after the end of the warm up, 15s after completing the test, 2min/4min/6min/8min/10min after the test
rating of gastrointestinal stress	during the 3 weeks of study phase	1min before starting to drink the fluid, 2min before starting with the warm up, 2min before the test and 2min after having completed the 1500m
Rating of Perceived Exertion (RPE)	during the 3 weeks of study phase	15s after the end of the warm up, 15s after having completed the 1500m
Heart Rate	during study phase of 3 week (4 tests)	Heart Rate measured from 2min before the test until 5min after the 1500m-test.
Oxygen Consumption	during 3 weeks of study phase	oxygen consumption (VO2(ml/min/kg), VCO2(ml/min), RER (VCO2/VO2)) starting of the measurement is 2min before the start of the 1500m and ends 2min after having completed the 1500m

Trial Locations

Locations (1)

Swiss Paraplegic Centre; 🇨🇭 Nottwil, Lucerne, Switzerland