Comparison between Bubble Non Invasive Ventilation and Ventilator Non Invasive ventilation in babies more than 28 weeks
Not Applicable
- Conditions
- Health Condition 1: J988- Other specified respiratory disorders
- Registration Number
- CTRI/2023/05/052969
- Lead Sponsor
- Department of Neonatology Institute of obstetrics and Gynecology Madras Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
all Neonates more than 28 weeks of gestation and more than 1 kg ,with respiratory distress developed within 6 hours of life
Exclusion Criteria
Delivery room intubation
Major congenital /lethal anomalies
Birth asphyxia ,with APGAR score of less than 6 at 5 min
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Delivered distended pressure in Bubble NIPPV and Ventilator NIPPV in neonates more than 28 weeks of gestation with respiratory distressTimepoint: Pressure delivered will be measured at 0 , 12 hours and 24 hours after starting intervention
- Secondary Outcome Measures
Name Time Method Duration of respiratory supportTimepoint: total number of days on which baby on respiratory support ,weaned to room air;Failure of deviceTimepoint: pressure requiring more than 24/7 and 20/7 in ventilator NIPPV and Bubble NIPPV to maintain spo2 with one of the following ,ph 7.2 pCO2 60 mmHg , apnea more than 3 per hour , Apnea requiring Bag and Mask ventilation , spo2 less than 85 % with maximum seetting;Need of surfactant in pre term babyTimepoint: as CPG 2021 guidelines , spo2 more than 30 % on maximum setting of device;To compare the complicationsTimepoint: Feed intolerance , defined by vomiting more than 2 episodes and abdomen distension , Air leaks;total length of hospital stay in both groupTimepoint: total number of days after which baby discharged or dies