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Comparison of pressure versus volume control ventilation in one lung ventilatio

Phase 3
Recruiting
Conditions
Thoracic surgery.
Registration Number
IRCT20121107011398N15
Lead Sponsor
Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Patients candidates for thoracic surgery under one-lung ventilation
ASA physical class < or = class III
Patients with a body mass index between 20 - 35

Exclusion Criteria

Severe preoperative hypoxemia (SPo2 lower than 88% with room air)
Patient dissatisfaction

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Arterial blood oxygen pressure (PaO2). Timepoint: Before starting one-lung ventilation and for second time, 30 min after start of one-lung ventilation. Method of measurement: Arterial blood gas analysis.;Peak airway pressure. Timepoint: After tracheal intubation and then every 15 min during one-lung ventilation. Method of measurement: By airway pressure monitoring device included in anesthesia machine.;End-tidal pressure of CO2. Timepoint: Every 15 min during surgery. Method of measurement: By Capnograph monitoring.
Secondary Outcome Measures
NameTimeMethod
Dynamic compliance of respiratory system. Timepoint: After tracheal intubation and then every 15 min during one-lung ventilation. Method of measurement: Using the standard formula and tidal volume divided in airway pressure.;Respiratory dead space. Timepoint: After tracheal intubation and then 30 min after one-lung ventilation starting. Method of measurement: Calculation by the use of arterial and end tidal PCo2 pressure.
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