How Important Are Hematological Parameters in the Prognosis of Severe Covid-19 Patients?

Completed

• Conditions: COVID-19
• Interventions: Diagnostic Test: Hemogram

• Registration Number: NCT05650944
• Lead Sponsor: Hisar Intercontinental Hospital

Brief Summary

It is aimed to reveal the treatment and prognostic values by evaluating the differences in hematological parameters and indices, especially in dead Covid-19 cases.

Material Method: It is planned to retrospectively examine the hemogram parameters of 125 male, 44 female and 169 critical Covid-19 patients hospitalized between 01.03.2020 and 31.12.2021. Subjects were divided into 2 groups as deceased (77) and living (92) patients according to demographic data such as age and gender.

Statistical evaluation: All analyzes were SPSS 25.0, Kolmogorov Smirnov test was used to determine distribution, median and interquartile range (Tukey's Hinges Percentile) were used to summarize variables. The differences between the Independent-Samples Mann Whitney U Test and the data of the patient groups and the optimal cut-off values, sensitivity and specificity values will be determined by ROC analysis. It will be considered statistically significant when the p value is below 0.05 (with the two-tailed test)

Detailed Description

The aim of this study is to examine the effectiveness of routine laboratory complete blood count parameters and rates as diagnostic and prognostic criteria in severe COVID-19.

Study Timeline

• Study Start: 2020-03-01
• Primary Completion: 2021-12-31
• Study Completion: 2022-09-30
• Status Verified: 2022-12
• Study First Submitted: 2022-12-02
• Study First Submitted QC: 2022-12-13
• Last Update Submitted: 2022-12-13
• Study First Posted: 2022-12-14
• Last Update Posted: 2022-12-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 125

Inclusion Criteria

1. Patients over the age of 18
2. Critical patients taken to intensive care
3. The length of stay in the ICU is more than 24 hours

Exclusion Criteria

1. Patients under 18 years of age (2) Patients with hematological malignancies (3) The length of stay in the ICU is less than 24 hours.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Covid-19 Non-survivor groups	Hemogram	Hematological parameters in patients with severe COVID-19 who have died.
Covid-19 Survivor groups	Hemogram	Covid-19 survivor groups are hematological parameters

Primary Outcome Measures

Name	Time	Method
Hematological parameters in the prognosis of severe Covid-19 patients.	2020-2021	Hemogram values of the deceased and surviving patients participating in the study were compared.

Trial Locations

Locations (1)

Hisar Hospital Intercontinental; 🇹🇷 Istanbul, Turkey