Induction of labour in women with term premature rupture of membranes.

Not Applicable

Recruiting

• Conditions: Pregnancy and Childbirth; Induction of labour in pregnant women with term premature rupture of membranes.

• Registration Number: PACTR201211000447393
• Lead Sponsor: Department of Obstetric and Gynecology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-10-30
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 110

Inclusion Criteria

Confirmed gestational age (32-42 weeks gestation)determined last menstrual period or by ultrasound scan in the 1st trimester.
A singleton pregnancy with normal fetus in vertex presentation.
Premature rupture of membranes confirmed by visualizing a pool of amniotic fluid at a sterile speculum examination and AFI less than 5.
Absence of other indications for urgent induction of labor
No signs of active labor, no abdominal pain on admission.

Exclusion Criteria

Known hypersensitivity or any contraindications to prostaglandins (e.g.gluoma or sickle cell disease).
Multiple pregnancy.
Multiparity
Contraindication to vaginal birth such as previous uterine surgery, contracted pelvis or malpresentation.
Estimated fetal weight more than 4 kg or less than 2 kg
Placenta previa or unexplained vaginal bleeding.
Evidence of chorioamnionitis.
Medical diseases e.g. cardiovascular disease or chronic renal failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified