The Effect of Vitamin D and Calcium Supplement on Overall Body Bone Density and Implant Stability in Posterior Maxilla

Not Applicable

Completed

• Conditions: Dental Implant

• Registration Number: NCT06673485
• Lead Sponsor: Al-Azhar University

Brief Summary

The aim of the study is to evaluate the effect of Vit D and Calcium administration on allogragt bone maturation radiographically and histomorphometercally in maxillary sinus augmentation in cases of D4 bone density.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-02
• Primary Completion: 2023-03-01
• Study Completion: 2023-03-01
• Status Verified: 2024-10
• Study First Submitted: 2024-10-13
• Study First Submitted QC: 2024-11-02
• Last Update Submitted: 2024-11-02
• Study First Posted: 2024-11-05
• Last Update Posted: 2024-11-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Patient with residual bone height from 5 : 8 .
• Patient with insufficient Vit D levels.
• Patient with D4 bone density.

Exclusion Criteria

• Patients that have aproporiate amount of Ca and Vit D.
• Sinus pathology that precludes routine sinus augmentation.
• Heavy smookers patients.
• Systemic diseases that interfere with bone maturion.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The Implant Stability Quotient	Immediate post-operative, and 6 Months post-operative	The Implant Stability Quotient (ISQ) will be assessed using the Osstell device, which provides a stability score ranging from 0 ISQ to 100 ISQ. Higher ISQ values indicate greater implant stability, with 0 ISQ representing the lowest stability and 100 ISQ the highest. This measure allows for consistent, objective assessment of implant stability across time points.

Secondary Outcome Measures

Name	Time	Method
DXA Scan	pre-operative, and 6 Months post-operative	DXA scan was carried out to T-score. minimum is - 4 and maximum is 1. the more T-score, the better the bone density.
Vitamin D serum levels	Pre-operative, and 6 Months post-operative	Vitamin D serum levels (nanograms per milliliter (ng/ml)) will be represented as values, with higher values indicating a better vitamin D status. This measurement provides an objective assessment of vitamin D levels across participants.
Calcium Serum Level	Pre-operative, and 6 Months post-operative	Calcium serum levels (milligrams per deciliter (mg/dl)) will be measured, with higher values indicating better calcium status within the physiological range. This measurement provides an objective assessment of calcium levels across participants, allowing for consistent evaluation of calcium status.

Trial Locations

Locations (1)

Alazhar University; 🇪🇬 Assiut, Egypt