se of cold preservative in inducing hypothermia of newborns with encephalopathy

Not Applicable

• Conditions: ischemic hypoxic episma encephalopathy.

• Registration Number: IRCT20190204042609N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Apgar score less than 5 in 10 minutes after the birth or need of the baby to continue the regenerative process (including ventilation with mask and intubation) until 10 minutes after birth or acidosis in the first hour after birth (PH in umbilical cord or arterial blood and Or capillary blood less than 7) or a base deficiency greater than 16 millimoles / liter in any of the blood samples within 60 minutes of the first birth
Clinical manifestations of moderate to severe postpartum encephalopathy

Exclusion Criteria

Parental dissatisfaction at each stage of induction cooled therapy
The infant's center temperature reaches more than 38 degrees Celsius
Neonatal abnormalities require surgery
Newborns with obvious anomalies require immediate intervention such as cyanatoid heart disease
In case of possible complications of treatment, a newborn resuscitation, such as severe bradycardia associated with apnea

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infants with moderate to severe HIE. Timepoint: Duration 48 to 72 hours of birth. Method of measurement: Clinical-Biochemical.