Evaluation of the effect of maintenance serum with the amount of sodium at the limit of isotonic saline on sodium level, blood pressure and acidosis in admitted patients.
- Conditions
- Condition 1: Hypertension. Condition 2: Influence of the maintenance fluid (normal vs. half saline) on blood sodium level.Other secondary hypertensionHypo-osmolality and hyponatremiaI15.8E87.1
- Registration Number
- IRCT20230414057904N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Age between 3 months and 18 years
Need for injectable serum
Sodium level below 130 mmol/L
Sodium level above 150 mmol/L
Having diabetes insipidus
Diabetic ketoacidosis
Kidney disease requiring dialysis
Suffering from the disease of high sodium urinary excretion(Addison's disease, congenital adrenal hyperplasia, Barrett's syndrome)
Patients before or after neurosurgery
Require chemotherapy hydration
Severe liver disease
Patients who are likely to receive maintenance serum for less than 6 hours
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ?Blood Sodium level. Timepoint: 6,24,48, and 72 hours. Method of measurement: Blood lab test, with the same kit for all patients.;Blood pressure. Timepoint: Every hour. Method of measurement: Non-invasive blood pressure monitoring, with appropriate cuff size.;Blood PH. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.;Blood bicarbonate level. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.
- Secondary Outcome Measures
Name Time Method