Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars

Not Applicable

• Conditions: Acne Scars
• Interventions: Procedure: Laser therapy

• Registration Number: NCT03850925
• Lead Sponsor: Dongtan Sacred Heart Hospital

Brief Summary

This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.

Detailed Description

This trial is a 17-week, prospective, randomized split-face study that compares the results between two facial sides either receiving the picosecond 1064-nm laser or nonablative fractional laser treatment for atrophic acne scar.

Study Timeline

• Study First Submitted: 2019-02-20
• Study First Submitted QC: 2019-02-21
• Study First Posted: 2019-02-22
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-30
• Study Start: 2019-05-01
• Last Update Posted: 2019-05-02
• Primary Completion: 2020-04-30
• Study Completion: 2020-04-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Subjects with facial atrophic acne scars
• Subjects who observe the schedules and protocols of the clinical trial
• Subjects who give informed consent to participate in the clinical trial

Exclusion Criteria

• Subjects who have active acne under treatment
• Subjects who had received any other treatments for acne scarring for 6 months prior to the first treatment
• Subjects who underwent other treatments including chemical, mechanical or laser resurfacing during the study period
• Subjects who have current acute illness
• Subjects who are considered inappropriate for the clinical trial under the judgement of investigators

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fractional laser	Laser therapy	Intervention: four consecutive sessions of nonablative fractional laser at 3-week intervals
Picosecond laser	Laser therapy	Intervention: four consecutive sessions of 1,064-nm picosecond laser at 3-week intervals

Primary Outcome Measures

Name	Time	Method
Changes in the mean of the ECCA grading scale	Week 17	The ECCA (échelle d'évaluation clinique des cicatrices d'acné) grading scale: minimum score 0; maximum score 270; higher values represent a worse outcome.

Trial Locations

Locations (1)

Dongtan Sacred Heart Hospital, Hallym Universtiy College of Medicine; 🇰🇷 Hwaseong-si, Gyeonggi-do, Korea, Republic of