Automatic weaning with adaptive support ventilation (ASV): effect on nurse workload and duration of spontaneous ventilation until extubatio
- Conditions
- Mechanical ventilationRespiratory
- Registration Number
- ISRCTN65935865
- Lead Sponsor
- Academic Medical Centre (AMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 128
1. Planned uneventful cardiac surgery i.e. coronary artery bypass graft (CABG)
2. Following receipt of verbal and written information about the trial, the patient must provide signed and dated informed consent before any trial related activity is carried out
1. History of pulmonary disease
2. History of pulmonary surgery
3. Valve surgery
4. Arrival at the IC-unit with IABP or inotropes at a more then usual rate (in ml per hour: dopamine (4), norepinephrine (4), dobutamin (4) or epinephrine [any rate])
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Number of arterial blood gas (ABG) analyses<br>2. Number of audible alarms<br>3. Number of manual changes in the ventilator settings, including:<br>3.1. Switches from PC to PS (only in the control group)<br>3.2. Changes in minute ventilation (only in the ASV group)<br>3.3. Lowering of PS-level (only in the control group)<br>4. Duration of period of spontaneous mechanical ventilation<br>5. Duration of total period of tracheal intubation
- Secondary Outcome Measures
Name Time Method o secondary outcome measures